Test your medical knowledge each month with questions from The Medical Knowledge Self-Assessment Program庐 (MKSAP)
MKSAP has been trusted by internists since 1967 as the best resource for updating knowledge. MKSAP 19, available in Complete, Digital, and Print packages, consists of 11 comprehensive text chapters with related multiple-choice questions. You'll find 1,200 completely new questions to help you identify learning gaps, stay current, and gain the knowledge you need to provide the best possible patient care. MKSAP 19's original and high-quality questions evolve out of case studies and patient scenarios based on the latest evidence.
For more information on MKSAP 19, or to order your copy, visit
MKSAP 19 Q & A
A 35-year-old woman is evaluated for a 2-month history of fatigue, cold intolerance, constipation, and menorrhagia. She has no recent history of iodinated contrast or iodine supplementation. She takes no medications.
On physical examination, other than a pulse rate of 56/min, vital signs are normal. BMI is 22. The thyroid is firm and diffusely enlarged two times the normal size. Also noted are dry cool skin and dry coarse hair. No thyroid nodules are palpated.
Laboratory studies show a thyroid-stimulating hormone level of 12 渭U/mL (12 mU/L).
Which of the following is the most appropriate next diagnostic test?
A: Free thyroxine measurement
B: Free triiodothyronine measurement
C: Thyroid peroxidase antibody titer
D: Thyroid ultrasonography
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