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MKSAP 19 Q & A
A 48-year-old woman is evaluated for easy bruising. She has no history of gingival bleeding, menorrhagia, or bleeding following procedures. Medical history is notable only for systemic lupus erythematosus. Medications are prednisone, hydroxychloroquine, and NSAIDs as needed.
On physical examination, vital signs and examination findings are normal.
Laboratory studies show an activated partial thromboplastin time of 38 seconds, platelet count of 190,000/渭L (190 脳 109/L), and prothrombin time of 12.5 seconds.
Which of the following is the most appropriate diagnostic test?
A: Factor VIII inhibitor titer
B: Factor XI level
C: Factor XII level
D: Mixing study
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